all-thats-interesting:

The Nightmares Of Children, Recreated

This photo series by Arthur Tress is called “The Dark Side Of Dreams”. In it, he attempts to recreate the nightmares of children, and succeeds in giving us all nightmares. These are some seriously unsettling images: the longer you look, the creepier they become. Beautiful.

Source: Arthur Tress


artbyjeffreymeyer:

Jeffrey Meyer, Lookout Towers (2009), paper collage, 8 x 9 inches | website.
"   The world says: “You have needs — satisfy them. You have as much right as the rich and the mighty. Don’t hesitate to satisfy your needs; indeed, expand your needs and demand more.” This is the worldly doctrine of today. And they believe that this is freedom. The result for the rich is isolation and suicide, for the poor, envy and murder.   "
-Fyodor Dostoyevsky, The Brothers Karamazov (via fy-perspectives)
neurosciencestuff:

How the brain stabilizes its connections in order to learn better
Throughout our lives, our brains adapt to what we learn and memorise. The brain is indeed made up of complex networks of neurons and synapses that are constantly re-configured. However, in order for learning to leave a trace, connections must be stabilized. A team at the University of Geneva (UNIGE) discovered a new cellular mechanism involved in the long-term stabilization of neuron connections, in which non-neuronal cells, called astrocytes, play a role unidentified until now. These results, published in Current Biology, will lead to a better understanding of neurodegenerative and neurodevelopmental diseases.
The central nervous system excitatory synapses – points of contact between neurons that allow them to transmit signals – are highly dynamic structures, which are continuously forming and dissolving. They are surrounded by non-neuronal cells, or glial cells, which include the distinctively star-shaped astrocytes. These cells form complex structures around synapses, and play a role in the transmission of cerebral information which was widely unknown before.
Plasticity and Stability
By increasing neuronal activity through whiskers stimulation of adult mice, the scientists were able to observe, in both the somatosensory cortex and the hippocampus, that this increased neuronal activity provokes an increase in astrocytes movements around synapses. The synapses, surrounded by astrocytes, re-organise their architecture, which protects them and increases their longevity. The team of researchers led by Dominique Muller, Professor in the Department of Fundamental Neuroscience of the Faculty of Medicine at UNIGE, developed new techniques that allowed them to specifically “control” the different synaptic structures, and to show that the phenomenon took place exclusively in the connections between neurons involved in learning. “In summary, the more the astrocytes surround the synapses, the longer the synapses last, thus allowing learning to leave a mark on memory,” explained Yann Bernardinelli, the lead author on this study.
This study identifies a new, two-way interaction between neurons and astrocytes, in which the learning process regulates the structural plasticity of astrocytes, who in turn determine the fate of the synapses. This mechanism indicates that astrocytes apparently play an important role in the processes of learning and memory, which present abnormally in various neurodegenerative and neurodevelopmental diseases, among which Alzheimer’s, autism, or Fragile X syndrome.
This discovery highlights the until now underestimated importance of cells which, despite being non-neuronal, participate in a crucial way in the cerebral mechanisms that allow us to learn and retain memories of what we have learned.
europeansculpture:

Aristide Maillol - Torso, ca. 1906

lindsaylohoean:

"get your facts straight"

why not get your facts gay u homophobic piece of shit

hiphopclassicks:

Biggie x Charli Baltimore
tremored:

“damn bitch why u using teeth” 
art-documents:

Huang Yong Ping / 11 June 2002 – The Nightmare of George V (2002)

I disgust myself

bedforddane:

movie theatre bathrooms


art-documents:

Irish Pavilion at Venice Biennale 2013
Richard Mosse/The Enclave

cultmovie:

Would I Lie To You


adapto:

Body comparative #48 (1,2)